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Indeed, it was demonstrated that heterodimerization of 1-cysPrx with GSH-saturated GSTP results in S -glutathionylation of the oxidized cysteine in 1-cysPrx followed by subsequent spontaneous reduction of the mixed disulfide and restoration of enzymatic activity (Manevich et al., 2004)
Source: Grundmann, M., et al
Starting at 0.25 mg, your dose increases every four weeks over four to five months until you reach your therapeutic dose of 1.7 to 2.4 mg weekly
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